- Research Name Oncoimmunology Metabolomics
- Category Research Services
- Delivery Mode All Categories
Our Publications
An engineered IL-2 partial agonist promotes CD8+ T cell stemness.
GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation
Persistent CAD activity in memory CD8+ T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge.
Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function
Ullamcorper suscipit lobortis
Challenge & Solution
Oncoimmunology metabolomics is an emerging interdisciplinary field that combines insights from oncology, immunology, and metabolomics to understand how metabolic processes influence the interaction between cancer cells and the immune system. This comprehensive approach seeks to uncover the complex metabolic networks that underpin cancer development, progression, and the immune response to tumors.
Core Questions
Can metabolic biomarkers predict response to immunotherapy? And how does the metabolic reprogramming of cancer cells influence immune surveillance and response?
Identifying metabolic signatures that correlate with response or resistance to immunotherapy could help in the selection of patients likely to benefit from specific treatments. Understanding the metabolic strategies employed by cancer cells to evade immune detection and destruction is vital for developing therapies that can restore or enhance anti-tumor immunity.
What are the metabolic vulnerabilities of tumors that can be targeted to enhance immunotherapy?
Identifying metabolic pathways in cancer cells that are essential for their survival but dispensable for immune cells could lead to novel therapeutic strategies.
How can we manipulate the metabolism of immune cells to boost their function in the tumor microenvironment?
Strategies to enhance the metabolic fitness of immune cells in the TME could improve the efficacy of cancer immunotherapies.
Consultation and Customization
MyMeta Force in Complete Omics is committed to delivering tailored MFA solutions without compromising data integrity. We invite discussions on project-specific requirements, ensuring a bespoke service that meets your needs. Contact our specialists for a collaborative consultation.
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